振动光学活性（VOA）作为手性分子结构研究的核心技术，主要包括红外振动圆二色性（VCD）与拉曼光学活性（ROA）。历经四十年的学术发展与超过二十年的仪器与计算软件商业化进程，该技术已在化学各分支领域及各类手性分子的研究中取得丰硕成果，广泛应用于学术界与工业界。

为促进相关领域用户深入了解振动光学活性的最新进展、技术方法与前沿应用，推动该技术在手性科学、制药化学、生物分子结构等领域的更好的应用，技术部邀请了美国雪城大学Nafile教授和美国Biotools公司联合创始人Rina Dukor博士来中心作学术报告。

报告日期：2025年12月5日（星期五）

报告地点：五号楼第六会议室

报告时间：14:00-15:30

主 讲 人：Laurence A. Nafile 教授和Rina Dukor博士

报告题目：Advances in the Measurement and Application of Raman Optical Activity and Vibration Circular Dichroism Spectrometer

   报告摘要：Vibrational optical activity (VOA) is comprised principally of infrared vibrational circular dichroism (VCD) and vibrational Raman optical activity (ROA).1 After four decades of academic development and more than two decade of commercial availability of instrumentation and computation software, the field of VOA has amassed an impressive body of research across virtually all fields of chemistry and all classes of chiral molecules, in both academic and industrial settings. The principal application of VCD is the determination of absolute configuration and solution conformations in small organic molecules. as well as conformations of biological molecules. For,ROA most applications involve the conformation of biological molecules in solution. Recent advances in ROA involve the measurement of all four forms of ROA,(ICP,SCP,DCPI and DCPII)3 and the use of resonance ROA (RROA)4 in biological molecules with resonant chromophores to explore local chirality in this important class of molecules.Other recent applications of ROA will be discussed.